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Total dose: 0.9 mg/kg split into a bolus dose and infusion dose over 60 minutes.
Bolus dose: 10% of the 0.9 mg/kg treatment dose
Infusion dose: 90% of the 0.9 mg/kg treatment dose delivered over 60 minutes
| Patient weight (kg) | TNKase (mg) | Volume TNKase to be administered (mL) |
|---|---|---|
| <60 kg | 15 mg | 3 mL |
| ≥60 to <70 kg | 17.5 mg | 3.5 mL |
| ≥70 to <80 kg | 20 mg | 4 mL |
| ≥80 to <90 kg | 22.5 mg | 4.5 mL |
| ≥90 kg | 25 mg | 5 mL |
Please direct questions to Ivan Trang at cwtrang@gmail.com.